α,α'-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes.

نویسندگان

  • James L Galman
  • David Steadman
  • Sarah Bacon
  • Phattaraporn Morris
  • Mark E B Smith
  • John M Ward
  • Paul A Dalby
  • Helen C Hailes
چکیده

Transketolase mutants have been identified that accept aromatic acceptors with good stereoselectivities, in particular benzaldehyde for which the wild type enzyme showed no activity.

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عنوان ژورنال:
  • Chemical communications

دوره 46 40  شماره 

صفحات  -

تاریخ انتشار 2010